Berberine Complex – For Stable Blood Sugar & Insulin Sensitivity 10 plant extracts • dihydroberberine GlucoVantage® • 60 capsules
Berberine Complex is a dietary supplement focused on supporting normal blood glucose levels and carbohydrate metabolism. It combines dihydroberberine GlucoVantage®, selected plant extracts, and nutrients like chromium and biotin, which contribute to the normal utilization of sugars in the body.
Notice: The product was previously sold under the name Blood Sugar Breakthrough. You may therefore receive packaging with the old label – the content and composition are identical to the current version.
BiOptimizers – Berberine Complex – support for normal blood glucose levels and carbohydrate metabolism
Berberine Complex is a dietary supplement focused on supporting normal blood glucose levels. It uses a combination of dihydroberberine, chromium, biotin, and plant extracts for daily support of glucose and energy metabolism.
Each dose of two capsules provides 100 mg of dihydroberberine GlucoVantage® and 1,013 mg of a plant extract blend. Chromium contributes to maintaining normal blood glucose levels and macronutrient metabolism.
The blend contains carefully selected plant ingredients that complement the effects of dihydroberberine and micronutrients. Biotin supports normal energy metabolism and the utilization of nutrients from the diet.
Berberine Complex is taken in capsules that can be conveniently included with meals containing carbohydrates. It is suitable as part of an overall regimen that includes a balanced diet and regular exercise.
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Suitable for
Warning
According to EU regulations, we must state on our website:
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Follow the recommended daily dosage.
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The product is not suitable as a substitute for a varied diet and a balanced diet.
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If you are under medical care (ill), pregnant, or expecting pregnancy, consult the use of the product with a qualified nutritionist/doctor.
But! Every person has different needs, which means that the recommended daily dosage is not set in stone.
We, as sellers, are not qualified to advise you in any way. Always consult with a naturopath, holistic doctor, or another educated person who deals with traditional medicine (this can also be a classically educated doctor – rare exceptions).
Main benefits – Berberine Complex
- Support for normal blood glucose levels – thanks to the content of chromium for daily glycemic control.
- Carbohydrate and energy metabolism – biotin and chromium contribute to sugar utilization and energy production.
- 100 mg of dihydroberberine per dose – GlucoVantage® supplemented with 1,013 mg of a plant extract blend.
- Standardized plant ingredients – bitter melon, banaba, gymnema, and other extracts focused on glucose management.
- Convenient use with meals – 2 capsules with main meals containing carbohydrates can be easily included in the daily routine.
- Gluten and soy-free, in vegetarian capsules – suitable for users with these restrictions.
If you do not want to take capsules, you can find a liquid alternative in the form of Blood Sugar Support drops – Oregulin from North American Herb & Spice on pravebio.cz.
These are herbal drops focused on blood sugar management, which can be easily included in the daily routine alone or together with dietary adjustments.
Berberine Complex – who it makes the most sense for
- People who want to support normal blood glucose levels as part of an overall lifestyle.
- Those who regularly eat meals richer in carbohydrates and want to better manage glucose intake.
- Individuals who experience energy fluctuations after meals and want to support a more stable course throughout the day.
- Individuals focused on weight control who are already working with diet and exercise and are looking for a dietary supplement.
- Users who prefer gluten-free and soy-free supplements in vegetarian capsules and are interested in supporting carbohydrate metabolism.
Berberine Complex in practice: how it works with glucose in the body
- After taking a dose with food
- Capsules dissolve in the stomach, releasing dihydroberberine, chromium, biotin, and plant extracts.
- Absorption in the small intestine
- Substances are absorbed into the blood and begin to influence the utilization of glucose and metabolism of nutrients.
- Cellular work with glucose
- Overall effect during the day
- When taken regularly with meals, carbohydrates support more stable work with blood sugar as part of an overall lifestyle.
Why choose BIOptimizers
The brand BIOptimizers was founded in 2004 from the vision of Matt Gallant and Wade Lightheart – two former professional athletes who combined their own experiences with peak performance and a passion for science. Their goal was clear: to develop supplements that truly work, not only for athletes but for anyone who wants more energy, a clearer mind, and a stronger body.
From day one, BIOptimizers has stood out with an uncompromising focus on results and quality. Every formula is based on the latest scientific knowledge and tested in independent laboratories. The company collaborates with leading experts in biochemistry, functional medicine, and nutrition to ensure each product delivers measurable effects – from optimizing digestion to improving cognitive functions.
Today, BIOptimizers operates in more than 90 countries and is considered a leader in the field of digestive enzymes, probiotics, nootropics, and cellular energy. Thanks to transparency, customer education, and continuous innovation, it has built a reputation as a brand people trust because it brings real changes to everyday life.
Maximum efficiency
Products developed according to the latest studies, tested in practice, and focused on visible results – from the first day of use.
Quality ingredients
Carefully selected ingredients from verified sources, free from GMOs, gluten, soy, and artificial additives. Each batch undergoes independent purity and potency checks.
Science in practice
Collaboration with leading experts and long-term investments in research ensure that each formula meets the highest standards of functional medicine.
Responsibility to people and the planet
Minimizing plastics, recyclable packaging, and transparent disclosure of ingredient origins and test results – for trust that has solid foundations.
Founders of BIOptimizers
BIOptimizers was founded in 2004 by two friends – Wade Lightheart, a three-time champion in natural bodybuilding and nutrition expert, and Matt Gallant, a trained kinesiologist and experienced supplement developer. Their shared mission is clear: to create top-quality supplements that support digestion, energy, and overall vitality.
In the video below, they share key insights that change the view on common supplementation. They show that combining protein with enzymes can increase the absorption of amino acids by up to 1200%, meaning the body gets significantly more nutrients from food.
They also explain why magnesium is key to managing stress and how its deficiency disrupts the functioning of the nervous system. They emphasize the importance of gut health – an imbalance in the gut is often the cause of brain fog (a feeling of slowed thinking and lack of concentration), inflammation, and anxiety.
Composition
Complete composition
Main ingredients
Biotin; chromium (chromium picolinate); CyanthOx™ 30 (sea buckthorn fruit extract); Irvingia gabonensis (African mango seed); naringin; benfotiamine; R-alpha-lipoic acid; banaba (leaf extract); Gymnema sylvestre (leaf extract); fucoxanthin; bitter melon (fruit extract); GlucoVantage® dihydroberberine; Cinnulin PF® (cinnamon bark extract); InnoSlim® (extract of notoginseng and astragalus root).
Other ingredients
Hypromellose (vegetable capsule); rice fiber; rice extract; sunflower oil.
Summary of active substances
| Parameter | Per serving (2 capsules) | % DV* |
|---|---|---|
| Biotin | 2 mg | 6667 % |
| Chromium (chromium picolinate) | 400 µg | 1143 % |
| Proprietary blend (CyanthOx™ 30) | 638 mg | † |
| Bitter melon – fruit extract | 200 mg | † |
| GlucoVantage® dihydroberberine | 100 mg | † |
| Cinnulin PF® | 100 mg | † |
| InnoSlim® | 75 mg | † |
*DV – Daily Value. † Daily Value not established.
Usage
1 serving: 2 capsulesTake 2 capsules daily with a meal containing carbohydrates (such as lunch or dinner). Swallow the capsules with plenty of water and do not exceed the recommended daily dose.
Composition analysis and functional benefits
Dihydroberberine GlucoVantage®
What it is: A modern form of berberine with better absorbability.
Function: Upon absorption, it converts to berberine and acts on cellular pathways associated with glucose management.
Benefits: Allows for a lower dose of berberine in one capsule while targeting sugar metabolism.Chromium (chromium picolinate)
What it is: A trace element in a well-utilized form.
Function: Contributes to maintaining normal blood glucose levels and macronutrient metabolism.
Benefits: Provides officially recognized support for regulating blood sugar as part of a balanced diet.Biotin
What it is: A water-soluble B vitamin.
Function: Involved in normal energy metabolism and the utilization of nutrients from food.
Benefits: Supports the conversion of ingested carbohydrates and fats into usable energy.Bitter Melon – Fruit Extract
What it is: A plant extract standardized for charantin content.
Function: Traditionally used in recipes focused on managing glucose after meals.
Benefits: Complements the berberine complex with a long-used plant element.Banaba – Leaf Extract
What it is: An extract from banaba leaves containing corosolic acid.
Function: Included among plants used in blends for carbohydrate metabolism.
Benefits: Expands the spectrum of plant components in the blend alongside bitter melon and gymnema.Gymnema sylvestre – Leaf Extract
What it is: An Ayurvedic herb in a concentrated extract form.
Function: Used in products aimed at managing sugar cravings and glucose intake.
Benefits: Complements banaba and bitter melon effectively in one formulation.Cinnulin PF® – Cinnamon Bark Extract
What it is: A standardized cinnamon extract in a 20:1 ratio.
Function: Provides concentrated components of cinnamon bark used in products for managing blood sugar.
Benefits: Allows the addition of cinnamon in an effective, precisely dosed form without excess sugar.InnoSlim®
What it is: A patented blend of extracts from notoginseng and astragalus roots.
Function: Targets metabolic pathways related to nutrient intake and body composition.
Benefits: Complements the formula with adaptogenic elements that support the management of energy intake and utilization.
Other Ingredients
- CyanthOx™ 30 (sea buckthorn fruit extract) — a concentrated antioxidant extract that complements the blend with support against oxidative stress.
- Irvingia gabonensis (African mango seed) — a plant component used in formulas for fat and carbohydrate metabolism.
- Naringin — a citrus flavonoid that complements the blend with polyphenols.
- Benfotiamine — a well-absorbed form of vitamin B1 supporting energy metabolism of sugars.
- R-alpha-lipoic acid — a substance with antioxidant properties, included in blends for glucose metabolism.
- Fucoxanthin — a carotenoid from seaweed that expands the spectrum of plant antioxidants in the blend.
- Hypromellose (vegetable capsule) — forms the capsule shell, suitable for vegetarians and vegans.
- Rice fiber and rice extract — serve as a filler and technological component for a stable capsule form.
What does it mean for you?
The combination of all these ingredients means that the Berberine complex is not based on a single substance but on a combination of dihydroberberine, chromium, biotin, and multiple plant extracts. Together, they support the management of blood sugar and energy metabolism as part of an overall lifestyle based on diet and exercise.
Warnings
- Not intended for children. Pregnant and breastfeeding women should always consult a doctor before use.
- If you have diabetes, glucose metabolism disorders, or are taking medications to lower blood sugar, blood pressure, or blood thinners, consult a doctor before use.
- If you have other health issues or are taking any medications, consult a doctor or pharmacist before use.
- If adverse effects occur, discontinue use.
- Keep out of reach of children.
- Store in a dry, cool place, well-sealed, protected from moisture and heat.
- Do not use if the protective seal under the cap is damaged or missing.
What to buy?
- ✔︎ HUNTER & GATHER – C8 & C10 MCT Oil – pure MCT oil from C8 and C10 for quick energy from fats, helping to reduce reliance on quick sugars and support metabolism.
- ✔︎ L CELL – CaAKG - Capsules – a combination of CaAKG to support cellular metabolism, muscles, and overall vitality, suitable for long-term care of metabolic health.
- ✔︎ NATURTREU – Red Fermented Rice - fermented red rice for gentle support of liver, digestion, and daily fat metabolism as a supplement to care for blood lipids.
- ✔︎ CYTOPLAN – Vitamin B12 – biologically active forms of vitamin B12 for normal energy metabolism, nervous system function, and reduction of fatigue and exhaustion.
FAQ
Is Berberine complex suitable to use even if I don't have a diagnosed blood sugar problem?
Berberine complex is a dietary supplement for adults who want to support carbohydrate metabolism as part of an overall lifestyle. It is not intended to replace medications or medical care and is not meant to independently address suspected illnesses – if you have concerns about your blood sugar, it is advisable to discuss the situation with a doctor first and then consider incorporating a supplement like Berberine complex.
How does Berberine complex make sense if I'm already on a low-carb or ketogenic diet?
Users on a low-carb or ketogenic diet are already working with a lower intake of carbohydrates, but Berberine complex can be included with meals where there are more carbohydrates (such as social meals or traveling). The foundation remains diet, exercise, and overall routine – Berberine complex should be seen as a supplement to these steps, not as a replacement for a well-set diet.
Can Berberine complex be combined with other dietary supplements I am taking (such as magnesium, probiotics, or omega-3)?
In general, Berberine Complex can be combined with commonly used supplements such as magnesium, vitamins, omega-3, or probiotics, as it mainly targets carbohydrate metabolism and glucose management. However, it is advisable to be aware of the total amount and composition of supplements you are taking, and for more complex combinations or when taking medications, consult the inclusion of Berberine Complex with a doctor or pharmacist.
What should I do if I experience digestive discomfort or other side effects after taking Berberine Complex?
Some people may be more sensitive to berberine or concentrated plant extracts, and therefore may experience digestive discomfort (such as abdominal pressure, loose stools, or heartburn) after starting Berberine Complex. In such cases, it is reasonable to always take the capsules with food and possibly reduce the dose temporarily; if the discomfort persists, it is advisable to discontinue use and consult a doctor. In case of a significant reaction, do not resume Berberine Complex without professional consultation.
How does BiOptimizers develop its products?
The formulas are created with an emphasis on practical effectiveness, clear dosing, and the use of standardized extracts. The brand consistently communicates transparent composition and well-thought-out combinations of active ingredients.
Where does BiOptimizers source the ingredients for its products?
They emphasize verified suppliers and quality of raw materials — functional mushrooms, herbs, minerals, and enzymes. The goal is consistent purity and clearly stated parameters for each ingredient.
What does BiOptimizers specialize in?
The pillars include digestive enzymes, probiotics, minerals (e.g., magnesium), and blends for recovery, focus, and quality sleep — with an emphasis on practical use and clear labels.
How to incorporate BiOptimizers products into a daily routine?
Choose supplements based on your goal (e.g., digestion, energy, sleep). Follow the recommended dosage on the label and combine with a varied diet, hydration, and regularity for the best user comfort.
Additional parameters
| Category: | Glucose Metabolism & Blood Sugar |
|---|---|
| EAN: | 723098109713 |
| ? According to the problem: | Metabolism & blood sugar, Energy & vitality |
| Active ingredients: | Antioxidants |
| Does not contain: | Lactose-free, Gluten-free |
| For whom: | Unisex |
| Form: | Capsules |
| Key Feature: | Multi-ingredient blend, Vegan, Herbal, Natural-origin |
| Manufactured by: | BiOptimizers USA Inc. 5470 Kietzke Lane, Suite 300 Reno, NV 89511 |
| Country of origin: | Nevada, USA |
| Vhodné pro: | Gluten fee-Sugar Free-Lactose Free-Soy Free-GMO Free-Low Carb-Keto |
| Quantity: | 60 capsules |
Berberine Breakthrough Review From Bioptimizers - Control Your Blood Sugar Levels
BIOptimizers Berberine Breakthrough Benefits
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Bioptimizers is a nutritional supplement company founded by Wade Lightheart and his business partner Matt Gallant. Specializes in digestive enzymes, probiotics and other dietary supplements. The company was founded in 2004 and one of the first products to be launched was MassZymes. A revolutionary product created for protein digestion and muscle building.
Generally speaking, all Bioptimizers products are working towards a common goal ~ biological optimization or Biohacking. For example, some products like MassZymes can help digest protein to help increase the amount of muscle-building amino acids, while others like Mg. Breakthrough can contribute to muscle and nerve function.
Renowned dietary supplements for their:
- Innovative composition and high quality.
- Collaboration with experts and scientists.
- Specializing in digestion and gut health.
- Commitment to quality and continuous improvement.
- The powerful story and passion of the founders.
Dietary supplements
Enzymes
Probiotics and prebiotics
Collagens
Who is behind the BIOptimizers brand
Bioptimizers is an American nutritional supplement company run by its President Wade Lightheart and CEO Matt Gallant. Wade and Matt have been in business together since 2004 and have continually strived to release new groundbreaking products based on enzyme technology, probiotics and plant-based ingredients.
Today, they work together with a team of specialist scientists and nutritionists and invest a large amount of capital in developing the Bioptimizers brand to make it even better.
According to these two men, "Bioptimizers works with one of the best Chinese herb experts in the world, as well as the best scientists and enzyme formulators."
They also work closely with the "Burch University" in Sarajevo, Bosnia, and are constantly working to produce the best probiotics and gut health products.
To date, Wade, Matt and the Bioptimizers brand claim to have helped more than 65,000 people optimize their health and digestion.
So if you're looking for something that will really change your digestion, energy levels, brain function and overall physical well-being, then Bioptimizers shouldn't disappoint.
BIOptimizers was born out of pain and passion
Wade's passion and mission to help others optimize their health began when he witnessed his 23-year-old sister die from cancer. It was a heartbreaking experience that shaped his destiny. That's when he realized that health is the most precious thing we have in life.
Matt's passion and sense of helping others began when he helped his best friend lose 191 kg in 18 months. He watched as his friend's whole life was transformed because of it. Since he never had a girlfriend, he got married within a few years.
BIOptimizers products for real health optimization
Both Wade and Matt were coaches working with professional athletes and other top players. Both spent ten years in the gym helping people change their health.
Wade and Matt met at the gym, struck up a friendship and then began a business partnership that has lasted since 2004
Wade and Matt say: "That's right, in 2004 we started selling fitness programs, digestive enzymes and organic plant protein. Our obsession with creating best-in-class products and solutions is only getting stronger.
Our principle is: "If we can't create the best product in the category, forget it." We've always tried to make the best product possible.
We are ready to put absolutely EVERYTHING into one recipe. What does it mean? Our average cost per bottle is 200 to 400% higher than most of our competitors.
We use optimal, effective doses of the most researched ingredients. We know that once you experience the results, you will become a BiOptimizers fan for life.
Who are BIOptimizers products for?
For anyone looking for high quality dietary supplements that are FDA and GMP approved, third party tested and GMO free.
Bioptimizers specialize in better digestion. Those who have digestive health issues might find that what this company offers may definitely be able to help.
Specialized products like Herbal Power Flush, HCL Breakthrough and Gluten Guardian are truly unique in what they do.
There's also MassZymes for protein digestion, Blood Sugar Breakthrough for carbohydrate digestion and blood sugar control, Cognibiotics for mind and mood enhancement, and KApex for Keto/low-carb diet support.
A team of university experts in Bosnia
Our scientists create best-in-class formulations. We have established a partnership with Burch University in Sarajevo and invested heavily in the creation of a probiotics laboratory where several PhD students are working on the development of probiotics. We work with one of the best Chinese herb experts in the world, top scientists in the field of enzymes and one of the most experienced formulators in the world who has 40 years of experience in this field.
We never stop developing products and are constantly researching, testing and improving our recipes. Since 2004, we have helped more than 65,000 people optimize their health and digestion. We're working with some of the smartest people in the world to deliver on our commitment.
Monina Avdic, PHD
Probiotics Expert
D'Agostino
Scientific Advisor
Sabina Halilovic, PHD
Genetic Expert
Dženan Kovačič
Lab technician and expert in Molecular docking
Sarah Hotic
Lab technician in Plant Cell Culture
Muammar Dizdar
Master of Engineering Chemistry
Neira Crnčević
BSc in Genetics and Bioengineering
Haris Kolic
BSc in Genetics and Bioengineering
Dženeta Salčin
BSc in Biology, EcologyThe company is currently focusing primarily on improving and optimizing digestion.
BIOptimizers is a ''company for healthy digestion''.
Who are BIOptimizers products for?
Professional athletes and high performers
People who want to improve digestion
People with a passion for a healthy lifestyle
People looking for products with natural ingredients
BIOptimizers brand commitments
Continuous product development and improvement
Collaboration with the best experts and scientists
High cost of quality assurance components
Focus on the highest standards of safety and quality
Creating products to truly optimise health
